منابع مشابه
Genes, Chromosomes and Cancer
About 70 scientists recently attended the conference on " Aneuploidy and Cancer " in Oakland, CA, which was organized by P. Duesberg and D. Rasnick from the University of California, Berkeley, and generously sponsored by philanthropist Robert Leppo. The conference explored whether aneuploidy, i.e., specific ge-nomic imbalances, is a driving force behind the development of cancer. A century ago ...
متن کاملDissections and reconstructions of genes and chromosomes.
The Nobel lecture affords a welcome opportunity to express my gratitude and admiration to the numerous students and colleagues with whom I have worked and shared, alternately, the elation and disappointment of venturing into the unknown. Without their genius, perseverance and stimulation much of our work would not have flourished. Those who have worked with students and experienced the discomfo...
متن کاملGenes and chromosomes: control of development.
The past decade has witnessed immense progress in research into the molecular basis behind the developmental regulation of genes. Sets of genes functioning under hierarchical control have been identified, evolutionary conserved systems of genes effecting the cell-to-cell transmission of transmembrane signals and assigned a central role in morphogenesis have been intensively studied; the concept...
متن کاملGenes and chromosomes of Leishmania infantum.
During recent years, several Leishmania infantum genes have been cloned and characterized. Here, we have summarized the available information on the gene organization and expression in this protozoan parasite. From a comparative analysis, the following outstanding features were found to be common to most of the genes characterized: tandemly organized genes with conserved coding regions and dive...
متن کاملConnecting chromosomes, crisis, and cancer.
Cancer is a disease of impaired genome stability. The molecular forces that maintain genome integrity and sense altered chromosome structure are invariably subverted in cancer cells. Here, we explore the contrasting contributions of telomeres in the initiation and suppression of cancer and review the evidence supporting a role for telomere dysfunction as a mechanism driving the radical chromoso...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: CA: A Cancer Journal for Clinicians
سال: 1994
ISSN: 0007-9235
DOI: 10.3322/canjclin.44.3.133